Neuropsychological Test Norms in Cognitively Intact Oldest-Old

Neuropsychological data in nondemented oldest old: the 90+ Study.

Although the oldest old are the fastest growing segment of the population, little is known about their cognitive performance. Our aim was to compile a relatively brief test battery that could be completed by a majority of individuals aged 90 or over, compensates for sensory losses, and incorporates previously validated, standardized, and accessible instruments. Means, standard deviations, and p...

Gain in Brain Immunity in the Oldest-Old Differentiates Cognitively Normal from Demented Individuals

BACKGROUND Recent findings suggest that Alzheimer's disease (AD) neuropathological features (neuritic plaques and NFTs) are not strongly associated with dementia in extreme old (over 90 years of age) and compel a search for neurobiological indices of dementia in this rapidly growing segment of the elderly population. We sought to characterize transcriptional and protein profiles of dementia in ...

Becoming Oldest-old: Evidence

Cognitive performance in centenarians and the oldest old: norms from the Georgia Centenarian Study.

We present normative data from a large population-based sample of centenarians for several brief, global neurocognitive tasks amenable for frail elders. Comparative data from octogenarians are included. A total of 244 centenarians and 80 octogenarians from Phase III of the Georgia Centenarian Study were administered the Mini-Mental Status Examination, Severe Impairment Battery, and Behavioral D...

Oldest-Old Mortality in China

We find that the Kannisto model, a two-parameter logistic formula, fits Han Chinese death rates at oldest-old ages better than the Gompertz and four other models. Chinese death rates appear to be roughly similar to Swedish and Japanese rates after age 97 for both males and females. Because reports of age seem to be serviceably reliable up to age 100 and perhaps age 105 in China, we think that t...